Provides stricter enzyme-function hypotheses when higher-confidence EC assignment is needed.

EC Rigor

EC Rigor provides a stricter enzyme annotation signal than broad enzyme-class triage.

What It Does

The oracle prioritizes more specific enzyme-function hypotheses from sequence. It is designed for users who want a more conservative EC readout before deeper review.

Why It Matters

Specific enzyme annotation can guide pathway reconstruction, enzyme discovery, and experimental planning. False positives can be costly, so a stricter readout helps separate broad hints from candidates worth closer inspection.

Intended Use

Use EC Rigor when a workflow needs a conservative enzyme-function hypothesis and the next step is orthogonal confirmation.

Limitations

EC Rigor does not certify catalytic activity or substrate identity. Confirm important predictions with sequence search, active-site analysis, structural context, literature review, and biochemical assays.