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Research

Technical articles, manuscripts, and publication-ready research from Synthyra.

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  • Annotation Vocabulary
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Showing 11 of 11 items: 11 blogs, 0 papers

Dual Triangle Attention: Position Sense for Bidirectional Models

April 9, 2026

Blog
Research

Dual Triangle Attention: Position Sense for Bidirectional Models

Dual Triangle Attention keeps bidirectional context while giving transformers a built-in directional signal.

  • Attention
  • Transformers
  • Foundation Models
Accidental Taxonomists: When Protein Models Learn the Wrong Shortcut

October 24, 2025

Blog
Research

Accidental Taxonomists: When Protein Models Learn the Wrong Shortcut

Protein interaction models can look strong by learning species differences instead of interaction biology.

  • Protein Protein Interaction
  • Dataset Curation
  • Atlas
Atlas: Making Protein Screens Searchable

October 10, 2025

Blog
Research

Atlas: Making Protein Screens Searchable

Atlas turns sequence-first protein models into searchable maps for interaction, ligand, and annotation work.

  • Atlas
  • Protein Protein Interaction
  • Drug Discovery
  • Protein Function
Synteract-4: Interaction Prediction as Retrieval

September 18, 2025

Blog
Research

Synteract-4: Interaction Prediction as Retrieval

Synteract-4 reframes protein-protein interaction prediction as sequence-only representation learning at proteome scale.

  • Protein Protein Interaction
  • Synteract
  • Atlas
Protify: Model Choice As An Experiment

August 21, 2025

Blog
Research

Protify: Model Choice As An Experiment

Protify makes protein language model evaluation repeatable across tasks, datasets, and training strategies.

  • Protify
  • Benchmarking
  • Protein Language Models
DSM: Protein Generation with Masked Diffusion

June 9, 2025

Blog
Research

DSM: Protein Generation with Masked Diffusion

DSM brings masked diffusion to protein sequences, linking representation learning with biologically grounded protein generation.

  • Protein Generation
  • DSM
  • Protein Design
Synteract2: The Next Stage in Protein Interaction Prediction

April 22, 2025

Blog
Research

Synteract2: The Next Stage in Protein Interaction Prediction

Synteract2 extends sequence-based interaction modeling toward affinity and binding-site prediction while keeping evaluation caveats explicit.

  • Protein Protein Interaction
  • Synteract
  • Atlas
Translator: Broad Protein Annotation, Fast

March 18, 2025

Blog
Research

Translator: Broad Protein Annotation, Fast

Translator maps protein sequences into structured functional annotation hypotheses using the Annotation Vocabulary framework.

  • Annotation Vocabulary
  • Protein Function
  • Atlas
Annotation Vocabulary: Teaching Protein Models the Language of Function

July 30, 2024

Blog
Research

Annotation Vocabulary: Teaching Protein Models the Language of Function

Annotation Vocabulary turns protein properties into a structured language, giving models a cleaner bridge between sequence, function, and design.

  • Annotation Vocabulary
  • Protein Function
  • Atlas
cdsBERT: Why Codons Still Matter for Protein AI

September 15, 2023

Blog
Research

cdsBERT: Why Codons Still Matter for Protein AI

cdsBERT showed that protein models can learn useful biology by looking one layer earlier, at the codons that encode amino acids.

  • Codons
  • Protein Language Models
  • Foundation Models
Synteract: Predicting Protein Interactions from Sequence

June 7, 2023

Blog
Research

Synteract: Predicting Protein Interactions from Sequence

Synteract showed that large protein language models could help predict protein-protein interactions from amino acid sequence alone.

  • Protein Protein Interaction
  • Synteract
  • Atlas

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