Synthyra

For DNA synthesis providers and government

Advanced AI screening for biosecurity.

Synthyra finds sequences of concern that current DNA synthesis screening misses. Synthesis providers run it beside the checks they already have. Government agencies use the same models to predict how a pathogen acts on human cells.

Biosecurity screeningHost-pathogen prediction

Sequences of concern

Atlas flags sequences of concern that have no match in a screening list.

Host-pathogen maps

Atlas predicts which host proteins a pathogen acts on.

One API

Every service is an endpoint your systems and your agents can call.

What we do now

Two services and the platform under them.

Both services run on Atlas, our protein model. When the model improves, every service built on it improves at the same time.

01

Biosecurity screening

Active program

Atlas reads every sequence in an order and flags sequences of concern, including ones that match nothing in a screening list. Every flag comes with its reason.

See the approach

02

Host-pathogen interaction prediction

Active program

Atlas predicts which host proteins a pathogen acts on, and ranks the contacts a laboratory should test first.

See how

03

Atlas platform and API

Operating

The protein model behind both services. It predicts how proteins interact, what they do and what binds them, in the web app or through the API.

Open Discover

Platform & services

The platform under both services.

Atlas predicts how proteins interact and what they do, and shows each result in the context of the whole cell. Researchers use it today through the web app and the API.

Atlas system map tracing a protein perturbation across predicted cellular relationships

Interactive system views

See one change ripple through a cell.

01

Discover

Predicted interactions and functions for any protein, shown in the cell.

Open

03

Hypothesis

Ask which human proteins could fill a gap in a mechanism.

Early access

04

Demos

Pathogen screens and interactive maps built from real runs.

Explore

05

Models

The models and the evidence behind them.

Browse

06

Partner programs

Run a biosecurity or host-pathogen program with us.

Start

API

Call every service from your own systems.

Every service is an API endpoint. Our web app uses the same calls, and so can your pipeline or your agents.

Explore the API

Protein relationships

Which proteins a protein interacts with, within one organism or across two.

Ligand relationships

Which proteins a small molecule is predicted to bind, including the ones it should not.

Function and annotation

What a protein does, so a predicted interaction has a meaning.

Alignment

The closest known relatives of a sequence, with the alignments themselves.

System views

Results placed in the cell and in metabolism.

Where this goes

Where the same models go next.

Screening and host-pathogen prediction are the business today. The same models can also design proteins and small molecules, and that is where the company goes next.

Read our vision Design demos

The premise

A molecule can bind its target and still fail the patient.

The objective

We score a design on the effect it has on the whole system.

The evidence

Our earlier design system produced an EGFR binder that placed first on a worldwide leaderboard, at 630 pM.

The EGFR case study

News

Latest from Synthyra.

View all news

News · August 25, 2026

Stephen Wolfram Joins Synthyra as Advisor

Read

Paper · August 18, 2026

Atlas Host-Pathogen Interaction Report

Read

News · August 10, 2026

Diane Heiser Joins Synthyra as Advisor

Read

Our vision

Where Synthyra is going.

Why we start with biosecurity, and what we build after it.

Read our vision

Synthyra

Advanced AI screening for biosecurity.

Screening for sequences of concern, and prediction of how pathogens act on their hosts, built on one protein model.

Services

BiosecurityHost-pathogenPartner programs

Company

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