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Arpil 8th, 2025

Research

Synteract2 - The next stage in protein-protein interaction prediction

Full research results of the Synteract2 model.

  • Protein Protein Interaction
  • Synteract

Coming soon

Some teaser results:

Note: The haddock dataset is trimmed to examples where only two protein chains are involved in the binding affinity measurement.



Figure 1: Protein-protein affinity prediction error vs. previous state-of-the-art models.




Figure 2: Protein-protein affinity prediction correlations vs. previous state-of-the-art models.




Figure 3: Protein-protein binding site prediction metrics vs. state-of-the-art structure prediction model Boltz1. Our internal test set is utilized, Boltz1 may be trained on these PDB structures.


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